Elevated Levels of Serum Tumor Markers CEA and CA15-3 Are Prognostic Parameters for Different Molecular Subtypes of Breast Cancer
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منابع مشابه
Elevated Levels of Serum Tumor Markers CEA and CA15-3 Are Prognostic Parameters for Different Molecular Subtypes of Breast Cancer
BACKGROUND & AIMS The utility of measuring carcinoembryonic antigen(CEA) and cancer antigen 15-3 (CA15-3) levels in patients with breast cancer remains controversial. The present study aims to investigate the prognostic value of preoperative serum CEA and CA15-3 levels in breast cancer patients. METHODS Serum preoperative CEA and CA 15-3 concentration levels were measured in a total of 432 br...
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the value of clinical use of tumor markers cea and ca15-3 for early detection of recurrent breast cancer still is a controversial. this study was investigated relationship between tumor markers cea and ca15-3 and recurrence breast cancer. data regarding 147 women who had breast cancer were entered into the study. patients were reviewed for 120 months after treatment. maximum time for relapse wa...
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Detection of serum tumor markers has been developed as a non-invasive tool to assess treatment efficiency in different types of cancer. This study aims to investigate the role of preoperative serum tumor markers (CEA, CA125 and CA15-3) in the management of breast cancer, and their relationships with patients' clinicopathological parameters as well as different molecular subtypes. Altogether, 15...
متن کاملPrognostic Significance of Circulating Tumor Cells and Serum CA15-3 in Metastatic Breast Cancer
Breast cancer (BC) is the second leading cancer causing death in women (Siegel et al., 2012). Despite the widespread use of the screening methods, 5% of the cases were diagnosed at the advanced stage. Spread of the BC cells native of the primary location through circulation is one cause leading to metastasis (Jacob et al., 2007; Fehm et al., 2008). Presence of the circulating tumor cells (CTC) ...
متن کاملبررسی ارتباط بین مارکرهای سرمی HER2-neu،CA15-3 و CEA در بیماران کانسر پستان با مرحله تومور
Background & Aims : This study aimed to explore the correlation of serum level of HER2-neu, CA 15-3, and CEA with TNM staging for breast cancer Material & Methods : In this study serum samples of 50 patients with breast cancer were assessed with ELISA method for level of HER2-neu, CA15-3 and CEA preoperatively. After operation histopathologic specimens stained with Hematoxylin and E...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0133830